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In a clinical setting, options such as antioxidant therapy may be considered under professional guidance to support these natural functions

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Future research should also aim to disentangle the mechanistic interplay between S accumulation, sirtuin dysregulation, and impaired insulin signaling in PD, to identify which phytomolecules are most effective in counteracting mitochondrial stress, mitophagy defects, and neuronal apoptosis

Huan VD, Yamamura S, Ohtani K, Kasai R, Yamasaki K, Nham NT, Chau HM (1998) Oleanane saponins from Polyscias fruticosa

High respiratory activity results in raised levels of ROS originating from the electron transport chain